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Biohacking with Ed Hubbard, Part 2

Introduction

This is part 2 of Korus CEO Bryan Menell’s interview with Ed Hubbard on the techniques he has used (under his doctor’s care) for maximizing his health and wellness in unique ways.

Links to References in the Podcast

  1. CellTex Stem Cell Banking and Therapy
  2. Mecochymal Stem Cells (MSCs)
  3. NCBI Data on Cancer Prevention with Green Tea and Capsicum

Interview

So what are some things that Dr Grossman has worked with you on that have helped you with some really specific and actionable things that you’ve done?

Okay, well, let’s go from the easiest to maybe the most complicated. Okay. So first thing that a lot of doctors will tell you if you don’t have gastrointestinal issues in your family is you should probably be taking a baby aspirin, right? In the beginning doctors prescribed baby aspirin even though you can buy over the counter, also get it via a prescription, but they prescribed it for heart and circulatory issues, right? Because there’s a lot of anecdotal data back then and now there’s a lot of hard data that says it can help with our disease and in other circulatory problems. So roll the clock forward. Another couple decades after, people have been taking baby aspirin all this time and it turns out that their cancer rates have actually dropped quite a lot for certain cancers. Prostate cancer being one, you know, maybe 20-30% depending on the cancer types and the data is still a little bit inconclusive, but some of it has to do with lowering inflammation in the body and other things. So that’s an easy one for pretty much anybody to pick off and you don’t even really need a prescription for this stuff. You can just go buy baby aspirin at your favorite store. Maybe another step up from that is the diabetes drug Metformin. Metformin, is synthesized from, I think, French lilac flowers, small molecule there, and a way, way, way back in the old days, people would use it as a folk medicine when they had symptoms of diabetes, but there was no name for diabetes yet. They might say, hey, you know, I’ll make some tea out of this flower and it will make you feel better. Right? And some of these symptoms will go away. And so that turns out to be Metformin, so that’s the trade name and it’s a generic drug now and it’s been given to diabetics for probably 50 or 60 plus years now. I think it was originally prescribed in the UK or Europe, and then came to the US later. But not surprisingly, diabetics used to not live as long as people without diabetes. Give them Metformin, roll the clock forward a couple of decades. And now the diabetics, are living as long as people without diabetes. Okay. So that’s a great outcome for a drug. And Metformin doesn’t have many side effects if any side effects for most people. But here’s the interesting thing. Roll the clock forward another few decades and now the diabetics look to be outliving people without diabetes. And the only real longitudinal data difference is the fact that they’ve been taking Metformin. So when that data came out a lot of researchers said, well, something’s going on here. Let’s give metformin to some laboratory animals and see what happens when we take mice and given them Metformin. And then have our control group live a normal life without Metformin and normal chow and everything else. And it turns out those animals that were given Metformin would outlive the normal animals. So Metformin is the first drug now that has been approved for a FDA study for longevity or wellness. It’s called the fast trial. And I think it’s going to be pretty interesting. So that’s kinda the middle of one of the things that Dr Grossman has done. Kind of far out on the, on the outer edge is there are actually some blood tests now that can look for biomarkers of cancer in the blood. You take these blood tests and send the blood off to be analyzed and it comes back with either some cancer types identified from a tissue of origin. Or there’s a different test. There’s a few right? And I’ve taken a couple of them. There’s different tests that comes back, kind of a heat map scale of, you know, kind of green on one end and red hot and the other. And, you know, you kind of want to be as far down close to the green as you can, right. So I took one of these tests a couple of years ago. It’s called Oncoblot and it came back with tissue of origin markers for colon cancer. So that’s a pretty big concern. It turns out that there are a fair number of people that had taken the Oncoblot and probably 40 percent would come back with a biomarker for some tissue of origin cancer type. Not a huge surprise since a lot of people do develop cancer during our lifetimes. But you never want that blood test to come back with any tissue or origin marker, right? So there’s a paper in the NCBI database that you could go find about Oncoblot. And a supplement which is a combination of the active ingredient in green tea and capsaicin, which is the molecule that makes things taste spicy. Either one of those in a petri dish will make life very difficult for cancer cells and kill them. You put the two together and it’s like 100 times more effective at killing cancer cells. So the regimen is, I took the Oncoblot, came back with some biomarkers for cancer and I went on this regimen of the green tea and capsaicin combination for six months. You take the thing every four hours, which is kind of pain overnight, but they have a time release one now. And anyways, long story short, you do that for awhile. You retake the test and you know, you want to see come back clear. And in my case it came back clear and in most of the cases that, at least with Dr Grossman’s patients, he told me, most of them come back clear after that. So unlike maybe traditional medicine would say there’s absolutely nothing you can do. If you’re really, really catching these cancers early when they’re, you know, the size of a pinhead or something or just a colony of cells, it seems like maybe there is something you can do. And the paper that’s in the NCBI database actually had some pretty good data on it. I think it was, it was more than 100 patients that had done this: positive Oncoblot before do the regime, and then afterwards almost all of them had the Oncoblot come back clear. Pretty interesting stuff. Not a lot of people know about these cancer blood screening tests, but if you have cancer in your family that’s concerning, you should check them out.

People always say the earlier you discover these things, the more options you tend to have when you’re considering treatments.

Yeah, I mean even taking a supplement cocktail, which early on is I guess just a form of chemotherapy, right? But in a very natural way that has hardly any side effects for most people.

So taking a few preventative pills sounds relatively easy, but what sorts of really “out there” things are possible or that you’ve experienced?

Let me show you my bionic arm. Oh No, I’m just kidding. Well, let me tell you that’s the story of a CellTex quickly. So CellTex is a company in Houston, Texas, founded by an orthopedic back surgeon. His name is Stanley Jones, Dr Stanley Jones. And I met him when I went over to his shop a few years ago to get some abdominal fat extracted basically so that they could isolate these things called Mesenchymal Stem Cells. So they’re shorthand is MSCs. Okay. MSCS are basically there’s some controversy now, right? Whether they should be called stem cells are not or more maybe masters signaling cells or something else, but clearly they are doing some really interesting things in the body. And in mammals in general. I went to talk to the Celltex guys because I read a paper about a mouse study where they bio-engineered some mice. No, actually there were rats in this case. They bio-engineered some rats to have this condition called progeria, which is an accelerated aging disease. Actually, humans get this too. And it’s really tragic, you know, little kids that are eight, nine years old, they look like they’re 80 because the disease rapidly ages all of the systems that the, of a mammalian body. So you engineer these rats to have progeria and then you take some normal rats as a control. And then you see what happens when you give some of the progeria rats injections of MSCs or embryonic stem cells. Okay. Much easier to do in animals and humans, uh, you don’t treat them at all. And then you have some controls, right? So they run these rats through all these tests and as you would suspect, the rats that had progeria and are untreated, every one of those graphs look like you threw a rock off a tall building, right? It goes out like just a little bit and then drop straight to the ground. Right? And they, they’re dead, right in a very short period of time. The interesting thing was all the mice that were getting MSCs or embryonic stem cells had these lifespan curves that were just under the control group of mice that didn’t have progeria. It didn’t fix everything right? And it didn’t make them live longer than, than rats that didn’t have progeria. But the MSCs and the embryonic stem cells were repairing everything at such a fast rate that it almost made them live as long as the normal animals. Which is amazing, right? It’s crazy that, you know, I would have expected with embryonic stem cells, right, but not MSCs. And in fact the MSCs were almost as good as the embryonic cells. Not quite as good but close. So anyways, I read that paper, I thought, Jeez, I should, I should go look into this further. And I found Celltex and Dr Jones and went over Houston, had my fat extracted. They isolate MSCs, they bank them and then um, today it’s illegal to get this quantity of, of MSCs in the US, so you have to travel outside the country to get aa big quantity of your own adult stem cells back via an IV. And so they have it set up with a hospital in Cancun, Mexico. So periodically, I go down there and I get a big bag of my own MSCs. And the questions are always at this point, well, you know, how do you feel? Right? Does it make a difference in. The answer is I don’t really have any health problems right now. There’s plenty of examples of people that have health problems like juvenile rheumatoid arthritis, which can be a death sentence. They have treated a lot of those kids at Celltex and it puts them into remission after most of the doctors that were treating them said that they were going to be dead in their early twenties and now they’re married and having kids and all kinds of crazy stuff. So we know the MSCs have an effect. For me, it’s more about preventative maintenance, right? Planes don’t drop out of the sky because, you know, they are, they are maintained all the time, right. So that they just continue to function and never have a hiccup in the engine or the landing gear or anything else. So I view the MSCs as treatments as that form of preventive maintenance for me. I don’t want anything to go wrong. I don’t feel like I have anything wrong right now, but I want to keep it that way. I will say that, and it’s, it’s not a normal side effect of getting your own MSCs, but you know, I’m a little bit older, most people wear reading glasses. I could still get away without them and after a couple of the treatments I, I definitely think my eyesight improved a bit. There’s a few other things, but generally it’s working as I hope, which is just keep everything flying.

Just like the airplane example, it’s hard to do these things and prove at the end of the day, at the end of your life that these things helped or didn’t. You can’t prove a negative result. But, you know, chances are it’s helping in some way. You can’t measure it because there’s no “twin Ed” to do parallel studies with.

Yeah, right. It’s hard to say right now. Um, but look, I always view it. I’m like, if I don’t invest in and staying alive, then you know, what’s the point here? Right. I can’t do any more podcasts. I can’t enjoy my Starbucks coffee and be with my kids and my wife, and so, I mean, you got, that’s number one, right? Like if you’re, if you’re dead, then you know, everything is, is over. So I’m always trying to make sure I’m not going to be dead and uh, that’s important so that I can do everything else right.

A great health or wellness goal would be to try to live a quality life as long as you can and then just drop dead very quickly, right?

That healthspan curve is, that’s of ultimate importance, right? I mean right now the health span curve, you know, kind of looks good for the first 40 plus years. And then especially in first world countries, you know, there’s a lot of, there’s just a lot of disease types that are probably quite preventable, but you know, it puts you way down that curve early and then you are basically battling these conditions for the last 20, 30, maybe even 40 years of your life. Right? And their quality of life suffers and that’s no good. Right? So you want the curve to basically be flat all the way out until you’re almost dead and then drop off a cliff.

All this fueled by our very sedentary lifestyles and the abundance of cheap, fast food out there.

Yeah. And uh, lots of carbs, right?

Speaking of carbs, tell us about what your diet preferences are all these days.

Okay. So, my theory of a dieting is that there’s a lot of diet types, probably for good reason, right? Just like small molecule drugs don’t work for every single genome, right? And some small molecule drugs may work better for you than me, right? There’s probably an optimal, a nonsteroidal antiinflammatory drug, right? An NSAID that I should take versus maybe what you should take, right? Maybe I should take Ibuprofen and you should take naproxen, but we don’t get down to that level, right, with people’s biology yet. Um, so I think diets are probably the same and that’s why there’s so many of them, right? Because some of them work great for some people and their genomes and some don’t. And uh, others work great for, for others. For me, if I cut out carbs and then everything is right with the world, the weight comes down, the blood work improves. My theory on, on my cholesterol is, you know, if I have lots of carbs floating around, my liver does its normal detoxing and filtering job. But then says, well, you know, yeah, I still have plenty of juice here to do something, let’s make cholesterol. Right? And so it makes cholesterol and my cholesterol is high. And when I cut out the carbs, you don’t have the simple sugars, the glycose anymore floating around in your blood, so your body flips over to burning ketones and ketone bodies and those get made by the liver. So when there’s no sugar floating around — this my theory, at least — my liver does its normal job of filtering and detoxing, but then says, well, Geez, I don’t have a lot of sugar around here for the body. Uh, instead of making cholesterol, go ahead and make ketones because that’s what I have to do right now. So it stays busy making ketones and not making cholesterol and my cholesterol goes down. Right. So for me, the, the Keto Diet generally is optimal. I know for a lot of people, pretty much nobody wants to hear that, right? Because everything’s got a lot of carbs in it. Ice Cream is especially bad for me. Right. But, anyways, it works for me. Iy probably doesn’t work for everybody but I’ve on this keto kick for awhile now and uh, yeah, works great.

It’s helped your numbers?

Helps my numbers a lot.

Well, Ed thank you so much for being on the podcast.

Thanks for having me. I hope this was useful for some of your listeners and you know, as always these are my experiences and your mileage may vary greatly. So make sure you talk to your doctor before you do any of these crazy things.

Absolutely.

Thank you very much.

Thanks.

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